Possible Exiguobacterium sibiricum Skin Infection in Human
نویسندگان
چکیده
tion of peste des petits ruminants virus and prospects for improved diagnosis and control.dence of peste des petits ruminants (PPR) virus circulation in Algeria (Sahrawi territories): outbreak investigation and virus lineage identification. To the Editor: The genus Exigu-obacterium was first described in 1983 by Collins et al., who characterized the species E. aurantiacum (1). Since then, 9 new species have been added: E. acetylicum, (2,3). The genus Exigu-obacterium belongs to the group of co-ryneform bacteria, which encompasses aerobically growing, non–spore-forming , irregularly shaped, gram-positive rods (2). Exiguobacterium spp. have been isolated from a wide range of habitats, including cold and hot environments (3). Although strains of Ex-iguobacterium spp. have been isolated from human clinical specimens (e.g., skin, wounds, and cerebrospinal fluid), the clinical significance of these bacteria is poorly understood (4). We present a case of cutaneous infection possibly caused by E. sibiricum. In January 2014, a previously healthy 66-year-old farmer was admitted to the Health Center of Molina de Aragón (Guadalajara, Spain) with a 7-day history of an ulcer on the dorsal surface of the second finger on his right hand with a painful black eschar surrounded by edema, greenish exudate, erythema, and a broken blister. The lesion had progressively increased in size. The patient was a hunter who had handled the skin of a deer and a wild boar 4 days before. He had no history of trauma or receipt of antimicrobial drugs. At admission, he was afebrile with no systemic symptoms. Cutaneous anthrax was suspected on the basis of the clinical appearance of the lesion and the pa-tient's contact with animals. An exudate sample was obtained for culture, and treatment with oral ciprofloxacin (500 mg/12 hour) was initiated. The Gram-stained sample showed leukocytes without organisms. Culture was performed according to standard practice. Colonies observed after 24 hours of incubation on blood agar in pure culture were gray but turned orange after 48 hours. The colonies appeared mucoid and were nonhemolytic. Gram staining revealed wide, short, non– spore-forming, gram-positive rods. The isolate was motile, catalase positive , oxidase negative, and it fermented glucose and lactose. Reactions for in-dole, urea, and bile esculin were negative. The strain did not grow on Mc-Conkey agar and was facultatively anaerobic. The strain was initially identified as Bacillus spp. and was sent to the National Reference Laboratory of Majadahonda (Madrid, Spain) for species identification. There, the isolate was identified as E. sibiricum by …
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